Monday, September 16, 2013

Diabetes drug enters clinical trial for Alzheimer's treatment

 Posted by Neill Abayon

A drug commonly used for treating diabetes may reverse symptoms of late-stage Alzheimer's disease and is now in the process of entering a major clinical trial.

Researchers from Lancaster University in the UK conducted a study revealing that the drug, liraglutide, may reverse memory loss in the late stages of Alzheimer's, as well as prevent the build-up of toxic plaques on the brain that contribute to symptoms of the disorder.

Liraglutide is from a class of drugs known as GLP-1 (Glucagon-like peptide-1) analogue. The drug is prescribed to those suffering from diabetes and is used to stimulate insulin production.

But the study, published in the journal Neuropharmacology, shows that the drug can also pass through the blood-brain barrier and protect brain cells.

The researchers tested the drug on the brains of 14 month-old mice who were suffering from late stage Alzheimer's disease. Liraglutide was injected into the mice over a 2-month period.

More here.

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