Saturday, July 19, 2008


Posted by Neill Abayon

While many new medications for alzheimer's disease are being tested,donepezil hydrochloride (Aricept) recently received approval by the U.S. food and Drug Administration. The drug approved to be safe and effective in clinical trials of patients with mild to moderate severed disease.
Like tecrine hydrochloride (cognex) - the first medication approved for alzheimer's - donepezil hydrochloride blocks the breakdown of acetychlorine, a critical brain chemical associated with memory. But the new drug appears to have fewer side effects than tacrine, which can elevate liver enzymes, requiring regular blood testing.
Still other research, focuses on promising therapies that might delay onset of the disease. Recent studies suggest that nonsteroidal anti-inflammatory drugs (NSAIDs) such as Ibuprofen, or the hormone estrogen might stave off Alzheimers. Also under investigation is vitamin E plus selegiline an antioxidant that boosts the brain chemical dopamine, and prednisone, a steroid that may have an NSAID-like effect.

1 comment:

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